Oncology drug discovery requires knowing pharmacological mechanisms and efficacies on human tumor cells. 3D BioOptima provides a comprehensive oncology drug discovery platform for assessment of cell-based potency and in vivo efficacy.
Cellular Assay Services
3D BioOptima’s human tumor cell line bank consists of over 100 cell lines, covering 18 types of tumors. We are offering proliferation assays on these tumor cell lines.
In Vivo Testing Services
Subcutaneous (s.c.) xenograft tumor models are valuable tools for assessing in vivo efficacy and investigating PK-PD relationship of potential anti-cancer drugs. 3D BioOptima offers a large panel of s.c. xenograft tumor models. Our experienced and professional scientific team will help our sponsors choose appropriate models for preclinical oncology studies.
You can contact us through the right side, we will assign a professional consultant to answer your questions.
The SPF and general animal rooms, with more than 600 square meters, can perform experiments on mice, rats, dogs, monkeys, rabbits, small pigs, and many other genera.
Oral gavage, sublingual administration, injection, topical application, whole blood collection, excreta collection, tissue collection, eye tissue collection, cerebrospinal fluid collection, bile duct intubation, etc.
A strict quality management system is in place to ensure the reliability of data and validity of research.
There are more than 400 sets of various instruments such as 16 sets of LC-MS/MS systems, 2 sets of MSD, analytical balances of 1 part in a million and 1 part in 100,000, respiratory anesthesia machines, IVC systems, various incubators, tissue homogenizers, centrifuges and so on.
In vitro metabolic studies, including metabolic studies based on liver microsomes, hepatocytes, liver S9, CYP enzymes, etc;
Analysis of biological samples for PK, tissue distribution and excretion experiments, development and validation of analytical methods, parameter calculations, etc.
The laboratory follows GLP (Good Laboratory Practice) and ISO standards to ensure data reliability and accuracy.
More than 100 bead cell banks have been established.
In vitro cell proliferation inhibition, Caco-2 permeability, and hepatocyte-related experimental studies can be performed.
The laboratory has a cell bank of more than 100 beads. The laboratory strictly follows the experimental practice to ensure the accuracy and reproducibility of the data.
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